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Article

Seizure susceptibility to various convulsant stimuli in dystrophin-deficient mdx mice.

Neuroscience research - 1 Sept 2004

De Sarro Giovambattista, Ibbadu Guido Ferreri, Marra Rosario, Rotiroti Domenicantonio, Loiacono Antonella, Donato Di Paola Eugenio, Russo Emilio

Abstract excerpt

In the present study, the susceptibility of the mdx mouse, a dystrophin-deficient genetic model of Duchenne muscular dystrophy (DMD), to various convulsant stimuli has been evaluated and compared to three related mice strains (C57BL/6J, C57BL/10 and DBA/2 mice). Animals were treated with chemical convulsants impairing gamma-aminobutyric acid (GABA) neurotransmission [pentylenetetrazole, picrotoxin, bicuculline,...

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Identifiers

PMID: 15288497
DOI: 10.1016/j.neures.2004.05.007

Genes

DMD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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