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Article

Seizure susceptibility to various convulsant stimuli of knockout interleukin-6 mice.

Pharmacology, biochemistry, and behavior - 1 Apr 2004

De Sarro Giovambattista, Russo Emilio, Ferreri Guido, Giuseppe Bruzzese, Flocco Maria Antonietta, Di Paola Eugenio Donato, De Sarro Angela

Abstract excerpt

In the present study, the susceptibility of knockout interleukin-6 (IL-6(-/-)) mice to various convulsant stimuli has been evaluated and compared with other three related mice strains. Animals were treated with chemical convulsants impairing the gamma-aminobutyric acid neurotransmission [pentylenetetrazole (PTZ), picrotoxin, bicuculline, methyl-6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate (DMCM),...

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Identifiers

PMID: 15099921
DOI: 10.1016/j.pbb.2004.01.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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