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Article

Two lines of transgenic mice expressing cre-recombinase exhibit increased seizure susceptibility.

Epilepsy research - 1 Mar 2013

Kim Tae Hwan, Richards Kay, Heng Julian, Petrou Steven, Reid Christopher A

Abstract excerpt

Conditional mouse models based on the Cre-recombinase (Cre)-loxP method are a powerful tool for determining the spatial and temporal function of genes in neuroscience research. The Emx1-Cre conditional model is designed to drive Cre expression in a predominantly excitatory neuron specific manner and the Dlx5/6-Cre mouse expresses Cre predominantly in cortical inhibitory neurons. The mouse models expressing the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23196213
DOI: 10.1016/j.eplepsyres.2012.10.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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