Genetically epilepsy-prone rats (GEPRs) and DBA/2 mice: Two animal models of audiogenic reflex epilepsy for the evaluation of new generation AEDs.

doi:10.1016/j.yebeh.2015.06.030

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Genetically epilepsy-prone rats (GEPRs) and DBA/2 mice: Two animal models of audiogenic reflex epilepsy for the evaluation of new generation AEDs.

Epilepsy & behavior : E&B - 1 Jun 2017

De Sarro Giovambattista, Russo Emilio, Citraro Rita, Meldrum Brian S

Abstract excerpt

This review summarizes the current knowledge about DBA/2 mice and genetically epilepsy-prone rats (GEPRs) and discusses the contribution of such animal models on the investigation of possible new therapeutic targets and new anticonvulsant compounds for the treatment of epilepsy. Also, possible chemical or physical agents acting as proconvulsant agents are described. Abnormal activities of enzymes involved in...

Topics

Acoustic Stimulation
Animals
Anticonvulsants
Disease Models, Animal
Epilepsy, Reflex
Genetic Predisposition to Disease
Kindling, Neurologic
Mice
Mice, Inbred DBA
Rats
Rats, Sprague-Dawley
Rats, Transgenic

Source

Open in PubMed

Identifiers

PMID: 26254980
DOI: 10.1016/j.yebeh.2015.06.030

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics