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Article

Genetic comparison of seizure control by norepinephrine and neuropeptide Y.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Oct 2001

Weinshenker D, Szot P, Miller N S, Rust N C, Hohmann J G, Pyati U, White S S, Palmiter R D

Abstract excerpt

Epilepsy is a disease of neuronal hyperexcitability, and pharmacological and genetic studies have identified norepinephrine (NE) and neuropeptide Y (NPY) as important endogenous regulators of neuronal excitability. Both transmitters signal through G-protein-coupled receptors, are expressed either together or separately, and are abundant in brain regions implicated in seizure generation. NPY knock-out (NPY KO) and...

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Identifiers

PMID: 11567066
PMCID: PMC6762890

Genes

NPY
DBH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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