Article

Analysis of Flurothyl-induced Seizures and Epileptogenesis in Mice with Targeted Deletions of Exons 3 and 4 in Dock7

2026-04-23

Abstract excerpt

Mutations in DOCK7 have been identified in individuals with epileptic encephalopathies. Given that epileptic encephalopathies are a set of disorders that result in seizure activity and associated cognitive and behavioral impairments, we investigated the role of Dock7 in seizure susceptibility and flurothyl kindling using the repeated flurothyl seizure model in mice. Male and female Dock7 +/+ and Dock7 △ex3-4/△e...

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Literature Corpus work: 4d7db95e-9311-5bda-8059-3e6b9c262f7d
DOI: 10.64898/2026.04.22.720243

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