Article
Case-only study of interactions between genetic polymorphisms of GSTM1, P1, T1 and Z1 and smoking in Parkinson's disease.
Neuroscience letters - 19 Aug 2004
Deng Yifu, Newman Beth, Dunne Michael P, Silburn Peter A, Mellick George D
Abstract excerpt
Current opinion contends that complex interactions between genetic and environmental factors play a role in the etiology of Parkinson's disease (PD). Cigarette smoking is thought to reduce risk of PD, and emerging evidence suggests that genetic factors may modulate smoking's effect. We used a case-only design, an approach not previously used to study gene-environment interactions in PD, specifically to study...
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