Article
Glutathione S-transferase mu, omega, pi, and theta class variants and smoking in Parkinson's disease.
Neuroscience letters - 21 Feb 2007
Wahner Angelika D, Glatt Charles E, Bronstein Jeff M, Ritz Beate
Abstract excerpt
GSTs are a family of inducible phase II enzymes that may play a neuroprotective role in Parkinson's disease (PD). GSTs may also modify PD risk by metabolizing compounds in cigarettes, as cigarette smoking is generally found to be associated with a decrease in PD risk. Using a population-based case-control study design, we examined polymorphisms of the mu, omega, pi, and theta classes of GST to elucidate the main...
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