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Article

Exploring gene-environment interactions in Parkinson's disease.

Human genetics - 1 Apr 2008

McCulloch Colin C, Kay Denise M, Factor Stewart A, Samii Ali, Nutt John G, Higgins Donald S, Griffith Alida, Roberts John W, Leis Berta C, Montimurro Jennifer S, Zabetian Cyrus P, Payami Haydeh

Abstract excerpt

The objective of this study was to explore combined effects of four candidate susceptibility genes and two exposures on Parkinson's disease (PD) risk; namely, alpha-synuclein (SNCA) promoter polymorphism REP1, microtubule-associated protein tau (MAPT) H1/H2 haplotypes, apolipoprotein E (APOE) epsilon2/epsilon3/epsilon4 polymorphism, ubiquitin carboxy-terminal esterase L1 (UCHL1) S18Y variant, cigarette smoking...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18210157
DOI: 10.1007/s00439-008-0466-z

Genes

APOE
MAPT
SNCA
UCHL1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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