Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GST polymorphisms, interaction with smoking and pesticide use, and risk for Parkinson's disease in a Japanese population.

Parkinsonism & related disorders - 1 Aug 2010

Kiyohara C, Miyake Y, Koyanagi M, Fujimoto T, Shirasawa S, Tanaka K, Fukushima W, Sasaki S, Tsuboi Y, Yamada T, Oeda T, Miki T, Kawamura N, Sakae N, Fukuyama H, Hirota Y, Nagai M

Abstract excerpt

Patients with idiopathic Parkinson's disease (PD) appear to have reduced capacity for detoxification of certain environmental compounds. The glutathione S-transferases (GSTs) are candidate genes for PD because they are involved in the metabolism of pesticides and cigarette smoke. We investigated the relationship of the seven GST polymorphisms (GSTM1 deletion, GSTT1 deletion, GSTP1 rs1695, GSTO1 rs4925, GSTO1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Environmental Exposure
Share to Glutathione Transferase
Share to Japan
Share to Odds Ratio
Share to Parkinson Disease
Share to Pesticides
Share to Population Groups
Share to Smoking

Source

Identifiers

PMID: 20472488
DOI: 10.1016/j.parkreldis.2010.04.009

Genes

GSTO1
GSTO2
GSTM1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GST polymorphisms, interaction with smoking and pesticide use, and risk for Parkinson's disease in a Japanese population.PMID 20472488Read ↗

Case-only study of interactions between genetic polymorphisms of GSTM1, P1, T1 and Z1 and smoking in Parkinson's disease.Semantic proximity Read ↗

Glutathione S-transferase mu, omega, pi, and theta class variants and smoking in Parkinson's disease.Semantic proximity Read ↗

A case-control study of Parkinson's disease and tobacco use: gene-tobacco interactions.Semantic proximity Read ↗

Genetic polymorphisms involved in dopaminergic neurotransmission and risk for Parkinson's disease in a Japanese population.Semantic proximity Read ↗

The interplay between environmental and genetic factors in Parkinson's disease susceptibility: the evidence for pesticides.Semantic proximity Read ↗

Parkinson's disease, pesticides, and glutathione transferase polymorphisms.Semantic proximity Read ↗

Nullity of GSTT1/GSTM1 related to pesticides is associated with Parkinson's disease.Semantic proximity Read ↗

Parkinson's disease and pesticides: A meta-analysis of disease connection and genetic alterations.Semantic proximity Read ↗

Genetic and environmental risk factors for Parkinson's disease in a Chinese populationSemantic proximity Read ↗

Gene-environment interactions in parkinsonism and Parkinson's disease: the Geoparkinson study.Semantic proximity Read ↗

Genome-wide gene-environment interaction analysis of pesticide exposure and risk of Parkinson's disease.Semantic proximity Read ↗

MDR1 C3435T polymorphism and interaction with environmental factors in risk of Parkinson's disease: a case-control study in Japan.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.