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Article

Deamidation affects structural and functional properties of human alphaA-crystallin and its oligomerization with alphaB-crystallin.

The Journal of biological chemistry - 22 Oct 2004

Gupta Ratna, Srivastava Om P

Abstract excerpt

To determine the effects of deamidation on structural and functional properties of alphaA-crystallin, three mutants (N101D, N123D, and N101D/N123D) were generated. Deamidated alphaB-crystallin mutants (N78D, N146D, and N78D/N146D), characterized in a previous study (Gupta, R., and Srivastava, O. P. (2004) Invest. Ophthalmol. Vis. Sci. 45, 206-214) were also used. The biophysical and chaperone properties were...

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PMID: 15284238
DOI: 10.1074/jbc.M405648200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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