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Article

UV-A-induced structural and functional changes in human lens deamidated alphaB-crystallin.

Molecular vision - 1 Feb 2008

Mafia Kerri, Gupta Ratna, Kirk Marion, Wilson L, Srivastava O P, Barnes Stephen

Abstract excerpt

PURPOSE: To determine comparative effects of ultraviolet (UV)-A irradiation on structural and functional properties of wild type (WT) alphaB-crystallin and its three deamidated mutant proteins (alphaB-Asn78Asp, alphaB-Asn146Asp, and alphaB-Asn78/146Asp). METHODS: Three deamidated mutants previously generated from recombinant WT alphaB-crystallin, using a site-specific mutagenesis procedure as previously described...

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Identifiers

PMID: 18334940
PMCID: PMC2255029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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