Article
Interaction of βA3-Crystallin with Deamidated Mutants of αA- and αB-Crystallins.
PloS one - 1 Jan 2015
Tiwary Ekta, Hegde Shylaja, Purushotham Sangeetha, Deivanayagam Champion, Srivastava Om
Abstract excerpt
Interaction among crystallins is required for the maintenance of lens transparency. Deamidation is one of the most common post-translational modifications in crystallins, which results in incorrect interaction and leads to aggregate formation. Various studies have established interaction among the α- and β-crystallins. Here, we investigated the effects of the deamidation of αA- and αB-crystallins on their...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
