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Article

Tissue‐specific and inducible Cre‐mediated recombination in the gut epithelium

1 Jul 2004

Abstract excerpt

We generated two complementary systems for Cre-mediated recombination of target genes in the mouse digestive epithelium and tested them with a Cre-reporter mouse strain. Cre was expressed under the control of a 9 kb regulatory region of the murine villin gene (vil-Cre). Genetic recombination was initiated at embryonic day (E) 9 in the visceral endoderm, and by E12.5 in the entire intestinal epithelium, but not in...

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PMID: 15282745
DOI: 10.1002/gene.20042

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