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Article

Lactoferrin-iCre: A New Mouse Line to Study Uterine Epithelial Gene Function

13 May 2014

Abstract excerpt

Transgenic animal models are valuable for studying gene function in various tissue compartments. Mice with conditional deletion of genes in the uterus using the Cre-loxP system serve as powerful tools to study uterine biology. The uterus is comprised of 3 major tissue types: myometrium, stroma, and epithelium. Proliferation and differentiation in each uterine cell type are differentially regulated by ovarian...

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PMID: 24823394
DOI: 10.1210/en.2014-1265

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