Article
A CK19(CreERT) knockin mouse line allows for conditional DNA recombination in epithelial cells in multiple endodermal organs.
Genesis (New York, N.Y. : 2000) - 1 Jun 2008
Means Anna L, Xu Yanwen, Zhao Aizhen, Ray Kevin C, Gu Guoqiang
Abstract excerpt
Cre/LoxP-mediated DNA recombination allows for gene function and cell lineage analyses during embryonic development and tissue regeneration. Here, we describe the derivation of a K19(CreERT) mouse line in which the tamoxifen-activable CreER(T) was knocked into the endogenous cytokeratin 19 locus....
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