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Article

Quantitative trait loci near the insulin-degrading enzyme (IDE) gene contribute to variation in plasma insulin levels.

Diabetes - 1 Aug 2004

Gu Harvest F, Efendic Suad, Nordman Sofia, Ostenson Claes-Göran, Brismar Kerstin, Brookes Anthony J, Prince Jonathan A

Abstract excerpt

Insulin-degrading enzyme (IDE) plays a principal role in the proteolysis of several peptides in addition to insulin and is encoded by IDE, which resides in a region of chromosome 10q that is linked to type 2 diabetes. Two recent studies presented genetic association data on IDE and type 2 diabetes (one positive and the other negative), but neither explored the fundamental question of whether polymorphism in IDE...

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Source

Identifiers

PMID: 15277398
DOI: 10.2337/diabetes.53.8.2137

Genes

IDE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Quantitative trait loci near the insulin-degrading enzyme (IDE) gene contribute to variation in plasma insulin levels.PMID 15277398Read ↗

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