Article
Investigation of an inducible nitric oxide synthase gene (NOS2A) polymorphism in a multiple sclerosis population.
Brain research bulletin - 30 Jul 2004
Tajouri Lotti, Martin Virginie, Ovcaric Micky, Curtain Rob P, Lea Rod A, Csurhes Peter, Pender Michael P, Griffiths Lyn R
Abstract excerpt
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) affecting most commonly the Caucasian population. Nitric oxide (NO) is a biological signaling and effector molecule and is especially important during inflammation. Inducible nitric oxide synthase (iNOS) is one of the three enzymes responsible for generating NO. It has been reported that there is an excessive production...
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