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Article

Genetic variation in nitric oxide synthase 2A (NOS2A) and risk for multiple sclerosis.

Genes and immunity - 1 Sept 2008

Barcellos L F, Ramsay P P, Caillier S J, Sawcer S, Haines J, Schmidt S, Pericak-Vance M, Compston D A S, Gabatto P, Hauser S L, Oksenberg J R

Abstract excerpt

Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system with a strong genetic component. Variation in the major histocompatibility complex on chromosome 6p21, specifically the HLA-DRB1*15 haplotype, is the strongest genetic factor for MS, yet it is estimated to account for only a portion of risk for the disease. Previous evidence has implicated the nitric oxide synthase gene...

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Source

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Identifiers

PMID: 18580885
DOI: 10.1038/gene.2008.41
PMCID: PMC4020442

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Genetic variation in nitric oxide synthase 2A (NOS2A) and risk for multiple sclerosis.PMID 18580885Read ↗

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