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Article

No association of inducible nitric oxide synthase gene ( NOS2A) to multiple sclerosis.

Journal of neurology - 1 May 2003

Blanco Yolanda, Yagüe Jordi, Graus Francesc, Saiz Albert

Abstract excerpt

Nitric oxide (NO) is a nonspecific inflammatory mediator that has been involved in the pathogenesis of multiple sclerosis (MS). The influence of the promoter polymorphism of inducible NO synthase gene ( NOS2A) on susceptibility and outcome was studied in 140 MS Spanish patients and 147 healthy controls matched for sex, age, and ethnicity. No association was found between MS susceptibility, course or outcome of...

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Identifiers

PMID: 12736741
DOI: 10.1007/s00415-003-1047-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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No association of inducible nitric oxide synthase gene ( NOS2A) to multiple sclerosis.PMID 12736741Read ↗

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No linkage or association of the nitric oxide synthase genes to multiple sclerosis.Semantic proximity Read ↗

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Variation of genes encoding nitric oxide synthases and antioxidant enzymes as potential risks of multiple sclerosis development: a preliminary study.Semantic proximity Read ↗

Genetic variation in nitric oxide synthase 2A (NOS2A) and risk for multiple sclerosis.Semantic proximity Read ↗

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