Article
Structure of the actin crosslinking core of fimbrin.
Structure (London, England : 1993) - 1 Jun 2004
Klein Michael G, Shi Wuxian, Ramagopal Udupi, Tseng Yiider, Wirtz Denis, Kovar David R, Staiger Christopher J, Almo Steven C
Abstract excerpt
Filamentous actin is organized into bundles and orthogonal networks by the fimbrin/alpha-actinin superfamily of F-actin crosslinking proteins. The crystal structure of the Arabidopsis thaliana and Schizosaccharomyces pombe fimbrin cores provides the first description of a functional F-actin crosslinking protein and highlights the compact and distinctly asymmetric organization of the fimbrin molecule, in which the...
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