Article

Allosteric Regulation of Human Plastins

2021-12-01

Abstract excerpt

<h4>ABSTRACT</h4> Plastins/fimbrins are conserved actin-bundling proteins contributing to motility, cytokinesis, and other cellular processes by organizing actin assemblies of strikingly different geometries as in aligned bundles and branched networks. We propose that this unique ability stems from an allosteric communication between plastins’ two actin-binding domains (ABD1/2) engaged in a tight spatial associat...

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Literature Corpus work: c55d9fa7-4f82-53ac-9333-d74584ee8606
DOI: 10.1101/2021.12.01.470822

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