Article
Genetically inspired in vitro reconstitution of Saccharomyces cerevisiae actin cables from seven purified proteins.
Molecular biology of the cell - 1 Mar 2020
Pollard Luther W, Garabedian Mikael V, Alioto Salvatore L, Shekhar Shashank, Goode Bruce L
Abstract excerpt
A major goal of synthetic biology is to define the minimal cellular machinery required to assemble a biological structure in its simplest form. Here, we focused on Saccharomyces cerevisiae actin cables, which provide polarized tracks for intracellular transport and maintain defined lengths while continuously undergoing rapid assembly and turnover. Guided by the genetic requirements for proper cable assembly and...
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