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Role of Mitochondrial Dysfunction in UV ‐Induced Photoaging and Skin Cancers

1 May 2025

Abstract excerpt

Ultraviolet radiation (UVR) is the most detrimental external factor that induces acute photodamage, photoaging and skin cancers, with complex underlying molecular mechanisms initiated mainly by increased DNA damage and reactive oxygen species (ROS) generation. Mitochondria are the main organelles in skin cells that produce ROS and energy and regulate various physiological and pathological signalling pathways....

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Genomics, phytochemicals, and oxidative stress
Redox biology and oxidative stress
Skin Protection and Aging

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40318065
DOI: 10.1111/exd.70114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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