Article
A major lung cancer susceptibility locus maps to chromosome 6q23-25.
American journal of human genetics - 1 Sept 2004
Bailey-Wilson J E, Amos C I, Pinney S M, Petersen G M, de Andrade M, Wiest J S, Fain P, Schwartz A G, You M, Franklin W, Klein C, Gazdar A, Rothschild H, Mandal D, Coons T, Slusser J, Lee J, Gaba C, Kupert E, Perez A, Zhou X, Zeng D, Liu Q, Zhang Q, Seminara D, Minna J, Anderson M W
Abstract excerpt
Lung cancer is a major cause of death in the United States and other countries. The risk of lung cancer is greatly increased by cigarette smoking and by certain occupational exposures, but familial factors also clearly play a major role. To identify susceptibility genes for familial lung cancer, we conducted a genomewide linkage analysis of 52 extended pedigrees ascertained through probands with lung cancer who...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.