Article
Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium.
Journal of the National Cancer Institute - 7 Jul 2010
Truong Therese, Hung Rayjean J, Amos Christopher I, Wu Xifeng, Bickeböller Heike, Rosenberger Albert, Sauter Wiebke, Illig Thomas, Wichmann H-Erich, Risch Angela, Dienemann Hendrik, Kaaks Rudolph, Yang Ping, Jiang Ruoxiang, Wiencke John K, Wrensch Margaret, Hansen Helen, Kelsey Karl T, Matsuo Keitaro, Tajima Kazuo, Schwartz Ann G, Wenzlaff Angie, Seow Adeline, Ying Chen, Staratschek-Jox Andrea, Nürnberg Peter, Stoelben Erich, Wolf Jürgen, Lazarus Philip, Muscat Joshua E, Gallagher Carla J, Zienolddiny Shanbeh, Haugen Aage, van der Heijden Henricus F M, Kiemeney Lambertus A, Isla Dolores, Mayordomo Jose Ignacio, Rafnar Thorunn, Stefansson Kari, Zhang Zuo-Feng, Chang Shen-Chih, Kim Jin Hee, Hong Yun-Chul, Duell Eric J, Andrew Angeline S, Lejbkowicz Flavio, Rennert Gad, Müller Heiko, Brenner Hermann, Le Marchand Loïc, Benhamou Simone, Bouchardy Christine, Teare M Dawn, Xue Xiaoyan, McLaughlin John, Liu Geoffrey, McKay James D, Brennan Paul, Spitz Margaret R
Abstract excerpt
BACKGROUND: Genome-wide association studies have identified three chromosomal regions at 15q25, 5p15, and 6p21 as being associated with the risk of lung cancer. To confirm these associations in independent studies and investigate heterogeneity of these associations within specific subgroups, we conducted a coordinated genotyping study within the International Lung Cancer Consortium based on independent studies...
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