Article
Cumulative effect of multiple loci on genetic susceptibility to familial lung cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Feb 2010
Liu Pengyuan, Vikis Haris G, Lu Yan, Wang Yian, Schwartz Ann G, Pinney Susan M, Yang Ping, de Andrade Mariza, Gazdar Adi, Gaba Colette, Mandal Diptasri, Lee Juwon, Kupert Elena, Seminara Daniela, Minna John, Bailey-Wilson Joan E, Amos Christopher I, Anderson Marshall W, You Ming
Abstract excerpt
BACKGROUND: Genetic factors play important roles in lung cancer susceptibility. In this study, we replicated the association of 5p15.33 and 6p21.33 with familial lung cancer. Taking into account the previously identified genetic susceptibility variants on 6q23-25/RGS17 and 15q24-25.1, we further...
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