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Article

G6PD is indispensable for erythropoiesis after the embryonic-adult hemoglobin switch.

Blood - 15 Nov 2004

Paglialunga Francesca, Fico Annalisa, Iaccarino Ingram, Notaro Rosario, Luzzatto Lucio, Martini Giuseppe, Filosa Stefania

Abstract excerpt

Glucose 6-phosphate dehydrogenase (G6PD) (EC 1.1.1.42) is an essential enzyme for the rapid production of NADPH, as required on exposure to oxidative stress. Mouse embryonic stem (ES) cells can produce all embryonic and fetal/adult cell types. By studying the in vitro differentiation of embryoid bodies produced from G6pdDelta ES cells that are totally unable to produce G6PD protein, we found that these cells are...

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Identifiers

PMID: 15271799
DOI: 10.1182/blood-2004-03-0835

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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