GATA-1 regulates growth and differentiation of definitive erythroid lineage cells during in vitro ES cell differentiation.

Article

GATA-1 regulates growth and differentiation of definitive erythroid lineage cells during in vitro ES cell differentiation.

Blood - 1 Dec 1998

Suwabe N, Takahashi S, Nakano T, Yamamoto M

Abstract excerpt

Although the importance of GATA-1 in both primitive and definitive hematopoietic lineages has been shown in vivo, the precise roles played by GATA-1 during definitive hematopoiesis have not yet been clarified. In vitro differentiation of embryonic stem (ES) cells using OP9 stroma cells can genera...

Topics

Animals
Cell Differentiation
Cells, Cultured
DNA-Binding Proteins
Erythroid-Specific DNA-Binding Factors
Erythropoiesis
GATA1 Transcription Factor
Gene Expression Regulation
Mice
Mutation
Transcription Factors

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