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Article

Enhanced phospholipase C stimulation and transformation in NIH-3T3 cells expressing Q209LGq-alpha-subunits.

The Journal of biological chemistry - 15 Sept 1992

De Vivo M, Chen J, Codina J, Iyengar R

Abstract excerpt

NIH-3T3 cells were transfected with cDNA encoding the native alpha-subunit of the G protein Gq(alpha q) or a mutant (Q209L) form of alpha q. Cells expressing Q209L-alpha q showed greatly enhanced basal phospholipase C activity. Stimulation of phospholipase C activity by prostaglandin F2 alpha or...

Topics

3T3 Cells
Animals
Base Sequence
Blotting, Western
DNA
Enzyme Activation
Fibroblasts
GTP-Binding Proteins
Mice
Molecular Sequence Data
Mutation
Transfection
Type C Phospholipases

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PMID: 1526966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1526966-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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