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Article

Inhibition of cell differentiation by G alpha q in the renal epithelial cell line LLC-PK1.

The American journal of physiology - 1 Apr 1998

Sun L, Weaver D J, Amsler K, Weiss E R

Abstract excerpt

LLC-PK1, an epithelial cell line derived from the kidney proximal tubule, was used to study the ability of the G protein alpha-subunit, G alpha q, to regulate cell differentiation. A constitutively active mutant protein, alpha qQ209L, was expressed using the LacSwitch-inducible mammalian expression system. Induction of alpha qQ209L expression with isopropyl-beta-D-thiogalactopyranoside (IPTG) enhanced...

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PMID: 9575800
DOI: 10.1152/ajpcell.1998.274.4.C1030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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