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Article

alpha-Synuclein-synaptosomal membrane interactions: implications for fibrillogenesis.

European journal of biochemistry - 1 Aug 2004

Jo Euijung, Darabie Audrey A, Han Kyung, Tandon Anurag, Fraser Paul E, McLaurin JoAnne

Abstract excerpt

alpha-Synuclein exists in two different compartments in vivo-- correspondingly existing as two different forms: a membrane-bound form that is predominantly alpha-helical and a cytosolic form that is randomly structured. It has been suggested that these environmental and structural differences may play a role in aggregation propensity and development of pathological lesions observed in Parkinson's disease (PD)....

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Identifiers

PMID: 15265037
DOI: 10.1111/j.1432-1033.2004.04250.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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