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Article

Dynamics of cell adhesion and motility in living cells is altered by a single amino acid change in E-cadherin fused to enhanced green fluorescent protein.

Cell motility and the cytoskeleton - 1 Sept 2004

Fuchs Margit, Hutzler Peter, Handschuh Gabriele, Hermannstädter Christine, Brunner Ingrid, Höfler Heinz, Luber Birgit

Abstract excerpt

E-Cadherin regulates epithelial cell adhesion and is critical for the maintenance of tissue integrity. In sporadic diffuse-type gastric carcinoma, mutations of the E-cadherin gene are frequently observed that predominantly affect putative calcium binding motifs located in the linker region between the second and third extracellular domains. A single amino acid change (D370A) as found in a gastric carcinoma...

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Identifiers

PMID: 15259055
DOI: 10.1002/cm.20019

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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