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Article

Overview on the Role of E-Cadherin in Gastric Cancer: Dysregulation and Clinical Implications

30 Jul 2021

Abstract excerpt

gene plays important roles in tumorigenesis as well as in tumor progression, invasion and metastasis. Full-length E-cadhrin tethered on the cell membrane mainly mediates adherens junctions between cells and is involved in maintaining the normal structure of epithelial tissues. After proteolysis, the extracellular fragment of the full-length E-cadhein is released into the extracellular environment and the blood,...

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PMID: 34422902
DOI: 10.3389/fmolb.2021.689139

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