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Article

EGFR regulates RhoA-GTP dependent cell motility in E-cadherin mutant cells.

Human molecular genetics - 1 Jul 2007

Mateus Ana Rita, Seruca Raquel, Machado José Carlos, Keller Gisela, Oliveira Maria José, Suriano Gianpaolo, Luber Birgit

Abstract excerpt

Gastric cancer associated E-cadherin germline missense mutations lead to significant functional consequences, in both the structural and signalling properties of the protein. In this study, we have characterized the effect of four E-cadherin germline missense mutations (T340A, A634V, P799R and V8...

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Source

Identifiers

PMID: 17510211
DOI: 10.1093/hmg/ddm113

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17510211-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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