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Article

Phenotypic sensitivity to activated protein C in healthy families: importance of genetic components and environmental factors.

British journal of haematology - 1 Aug 2004

Taralunga Claudia, Gueguen René, Visvikis Sophie, Regnault Véronique, Sass Catherine, Siest Gérard, Lecompte Thomas, Wahl Denis

Abstract excerpt

The relative importance of environmental factors and genetic components other than factor V Leiden on the sensitivity to activated protein C (APC) in healthy nuclear families was determined. We studied 149 European families (298 parents and 278 biological offspring aged more than 6 years). APC response was measured and expressed as normalized APC-sensitivity ratio (n-APC-SR). Subjects were genotyped for G1691A...

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PMID: 15257712
DOI: 10.1111/j.1365-2141.2004.05055.x

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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