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Article

Biological and genetic factors influencing plasma factor VIII levels in a healthy family population: results from the Stanislas cohort.

British journal of haematology - 1 Jan 2005

Morange P E, Tregouet D A, Frere C, Saut N, Pellegrina L, Alessi M C, Visvikis S, Tiret L, Juhan-Vague I

Abstract excerpt

The mechanisms underlying the variability of factor VIII (FVIII) levels are still poorly understood. The only receptor of FVIII identified so far is the lipoprotein receptor-related protein (LRP), which is thought to be involved in FVIII degradation. We aimed to characterize biological and genetic factors related to FVIII variability, focusing on coding polymorphisms of the LRP gene and polymorphisms potentially...

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Source

Identifiers

PMID: 15606554
DOI: 10.1111/j.1365-2141.2004.05275.x

Genes

VWF
ABO

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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