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Article

Heritability of plasma concentrations of activated protein C in a Spanish population.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jan 2009

Soria José M, Navarro Silvia, Medina Pilar, Souto Ramón, Buil Alfonso, Estellés Amparo, Fontcuberta Jordi, España Francisco

Abstract excerpt

The protein C anticoagulant pathway plays a crucial role in the regulation of fibrin formation. Protein C is activated on the surface of endothelial cells by the thrombin-thrombomodulin complex with the stimulation of the endothelial protein C receptor. The levels of circulating activated protein C reflect in-vivo protein C activation, and a low level of activated protein C is a risk factor for venous...

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Identifiers

PMID: 19129726
DOI: 10.1097/MBC.0b013e3282f9ae25

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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