Article
Genetic determinants of hemostasis phenotypes in Spanish families.
Circulation - 4 Apr 2000
Souto J C, Almasy L, Borrell M, Garí M, Martínez E, Mateo J, Stone W H, Blangero J, Fontcuberta J
Abstract excerpt
BACKGROUND: Recent studies have described genetic mutations that affect the risk of thrombosis as a result of abnormal levels of such hemostatic parameters as protein C, protein S, and the activated protein C resistance ratio. Although these mutations suggest that genes play a part in determining variability in some hemostasis-related phenotypes, the relative importance of genetic influences on these traits has...
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