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Article

Truncation of the mismatch repair protein PMS2 during the neoplastic transformation of human breast epithelial cells in vitro.

International journal of oncology - 1 Aug 2004

Balogh Gabriela A, Russo Irma H, Russo Jose

Abstract excerpt

Alterations in known mismatch repair (MMR) genes have been found in many cancers, such as in hereditary non-polyposis colorectal cancer syndrome (HNPCC), in addition to specific oncogenes and tumor suppressor gene abnormalities. We have reported mutations in the MMR genes hMSH2, hPMS2 and hMSH6 in human breast epithelial cell lines (HBEC). In hPMS2 we found a non-sense mutation in codon number 471 by a change of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cell Transformation, Neoplastic

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Source

Identifiers

PMID: 15254735

Genes

PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Truncation of the mismatch repair protein PMS2 during the neoplastic transformation of human breast epithelial cells in vitro.PMID 15254735Read ↗

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