Article
Mismatch repair and microsatellite instability in esophageal cancer cells.
International journal of cancer - 1 Mar 2001
Uchida N, Kumimoto H, Nishizawa K, Tokumasu S, Harada H, Shimada Y, Ishizaki K
Abstract excerpt
Using in vitro mismatch repair (MMR) assay, we have identified 3 of 22 esophageal cancer cell lines exhibiting reduced MMR activity. By means of gel-shift assay, decreased binding ability to GT mismatch and CA loop was observed in these 3 cell lines. However, we could not find any mutations in th...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
