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Article

A triad of subunits from the Gal11/tail domain of Srb mediator is an in vivo target of transcriptional activator Gcn4p.

Molecular and cellular biology - 1 Aug 2004

Zhang Fan, Sumibcay Laarni, Hinnebusch Alan G, Swanson Mark J

Abstract excerpt

The Srb mediator is an important transcriptional coactivator for Gcn4p in the yeast Saccharomyces cerevisiae. We show that three subunits of the Gal11/tail domain of mediator, Gal11p, Pgd1p, and Med2p, and the head domain subunit Srb2p make overlapping contributions to the interaction of mediator with recombinant Gcn4p in vitro. Each of these proteins, along with the tail subunit Sin4p, also contributes to the...

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Identifiers

PMID: 15254252
DOI: 10.1128/MCB.24.15.6871-6886.2004
PMCID: PMC444856

Genes

TBP
ARG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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