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Article

Studies of the RB1 gene and the p53 gene in human osteosarcomas.

Pediatric hematology and oncology - 1 Jan 2000

Scholz R B, Kabisch H, Weber B, Röser K, Delling G, Winkler K

Abstract excerpt

We analyzed 14 native osteosarcoma tissue samples for alterations of the tumor suppressor genes RB1 and p53 on the DNA level, and as far as possible, the RNA level. Southern blot analyses concerning both tumor suppressor genes were carried out in all osteosarcomas. In two cases we could demonstrate a deletion within the RB1 gene. DNA analysis of a third osteosarcoma patient revealed a rearrangement of the p53...

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Share to DNA Mutational Analysis
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 1524989
DOI: 10.3109/08880019209018328

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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