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Article

p53 gene mutations in osteosarcomas of low-grade malignancy.

Human pathology - 1 Nov 1998

Radig K, Schneider-Stock R, Haeckel C, Neumann W, Roessner A

Abstract excerpt

Alterations in tumor suppressor gene p53, localized on chromosome 17p13, are considered to play a significant role in the initiation and, to some extent, even in the progression of various malignant tumors. In this respect, investigations on conventional highly malignant osteosarcomas have shown a mutation rate of approximately 20%. However, currently, data on the mutation rate in the group of variant histology...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 9824113
DOI: 10.1016/s0046-8177(98)90263-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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