Article
[X protein variations of genotype B and C hepatitis B virus isolated from the patients with hepatocellular carcinoma].
Ai zheng = Aizheng = Chinese journal of cancer - 1 Jul 2004
Xu Xiao, Chen Wan-Nan, Zheng Da-Li, Huang Qing-Ling, Lin Xu
Abstract excerpt
BACKGROUND & OBJECTIVE: X protein was one of the most important pathogens of hepatitis B virus (HBV), and was crucial in the carcinogenesis of HBV related hepatocellular carcinoma (HCC). It was demonstrated that the infection of genotype B or C HBV would result in different clinical manifestations and pathological characteristics in HCC patients, however, it was under elucidation whether these differences related...
Topics
- Amino Acid Sequence
- Carcinoma, Hepatocellular
- Cloning, Molecular
- DNA, Viral
- Genotype
- Hepatitis B Antigens
- Hepatitis B virus
- Humans
- Liver Neoplasms
- Molecular Sequence Data
- Point Mutation
- Trans-Activators
- Viral Regulatory and Accessory Proteins