Article
A proteomics analysis of cellular proteins associated with HBV genotype-specific HBX: potential in identification of early diagnostic markers for HCC.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Aug 2005
Tan Tuan Lin, Chen Wei Ning
Abstract excerpt
BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common cancers in the world and causes approximately one million deaths every year. HCC is highly prevalent in Asia and closely associated with chronic hepatitis B virus (HBV) infection, with HBX protein playing a key role in the hepatocarcinogenic process. In addition, HBV genotypes B and C are clinically associated with different outcome of...
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