Article
Molecular characterization of hepatitis B virus X gene in chronic hepatitis B patients.
Virology journal - 8 Jul 2012
Barbini Luciana, Tadey Luciana, Fernandez Silvina, Bouzas Belen, Campos Rodolfo
Abstract excerpt
BACKGROUND: HBV-X protein is associated with the pathogenesis of HBV related diseases, specially in hepatocellular carcinomas of chronic patients. Genetic variability of the X gene includes genotypic specific variations and mutations emerging during chronic infection. Its coding sequence overlaps important regions for virus replication, including the basal core promoter. Differences in the X gene may have...
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