Hepatitis B virus X gene is implicated in liver carcinogenesis.

doi:10.1016/j.canlet.2009.04.010

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Article

Hepatitis B virus X gene is implicated in liver carcinogenesis.

Cancer letters - 1 Dec 2009

Koike Katsuro

Abstract excerpt

Hepatitis B virus (HBV) is a small hepatotropic and highly species-specific enveloped DNA virus. The carcinogenicity of this virus has become focused on the X gene and its coded X protein. The X protein itself is unable to bind to DNA directly, but works as a potent transcriptional activator thro...

Topics

Cell Transformation, Neoplastic
Genes, Viral
Hepatitis B virus
Humans
Liver Neoplasms
Mutation
Trans-Activators
Viral Regulatory and Accessory Proteins
Virus Integration

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