Article
Characterization of ciliated bronchial epithelium 1, a ciliated cell-associated gene induced during mucociliary differentiation.
American journal of respiratory cell and molecular biology - 1 Nov 2004
Yoshisue Hajime, Puddicombe Sarah M, Wilson Susan J, Haitchi Hans Michael, Powell Robert M, Wilson David I, Pandit Anita, Berger Ann E, Davies Donna E, Holgate Stephen T, Holloway John W
Abstract excerpt
Lung epithelial structure is altered in asthma; however, the precise mechanisms underlying epithelial repair, including differentiation from basal to columnar epithelial cells, are not well defined. In the course of random sequencing of a cDNA library from human lung biopsies, we have identified a novel gene, ciliated bronchial epithelium 1 (CBE1). Expression of CBE1 was induced during in vitro differentiation of...
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