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Article

BPIFB1 (LPLUNC1) is upregulated in cystic fibrosis lung disease

6 Jul 2012

Abstract excerpt

Although the biology the PLUNC (recently renamed BPI fold, BPIF) family of secreted proteins is poorly understood, multiple array based studies have suggested that some are differentially expressed in lung diseases. We have examined the expression of BPIFB1 (LPLUNC1), the prototypic two-domain containing family member, in lungs from CF patients and in mouse models of CF lung disease. BPIFB1 was localized in CF...

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PMID: 22767025
DOI: 10.1007/s00418-012-0990-8

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